Um, yeah, Johnny!
Costa and McCrae Normative Aging Study (1980):
The Normative Aging Study (Costa and McCrae, 1980) conducted at the Boston VA Outpatient Clinic followed men from their early 20s throughout adulthood. The only ones who had a midlife crisis (i.e., depression, despair, anger, blame, escapism, risky behavior) were ones who were also depressed and anxious in their late teens to early 20s. Once a crisis-prone individual, always a crisis-prone individual, according to this study.