Jim Conway's materials go into this a little bit. The book "Women in Midlife Crisis" has a section about a husband's MLC, and most of the rest of the book focuses on the different things that surround women's MLC. One of the differences that you will read about fairly often is that women tend to move through their MLC a little quicker than men. Obviously this is not true in every case, but it's a generalized statement you will see. In my opinion, it may be due to the way women deal with depression vs the way men deal with depression.
Regarding your wife's skin, hair, and sleep.......yes, those are all signs of stress, and directly related to MLC.
My ex-wife is in MLC and a good friend's ex-wife is also in MLC. From our experiences, here is some general info he and I have discussed......and by the way, our ex-wives do not know one another. He and I are friends, but our wives never met one another.
Both of our ex-wives filed for divorce and went through with it. Marriage counseling was attempted by both of us as well, and we have agreed that it did no good. Both our wives blamed the way they felt on us.....both said they wanted a new life.
My friend's ex-wife married the other man within six months of the divorce being final from my friend. Her current marriage has major issues and does not appear that it's going to make it, though that divorce has not been filed. After the divorce to my friend, he did not hear from her sometimes for a few months at a time. They are now in frequent contact (at least twice a week).
My ex-wife told me one time she was dating someone. She has said nothing about him since then, and I have never seen or met him. My ex-wife contacts me frequently, and there has not been a time where she has gone longer than about two weeks without initiating contact.
One thing seems true for men and women in MLC.....it takes time.