[Ready2Transform]

Agreed on all counts. Having had a very similar situation, even if they do go off of them, as mine did, if they don't taper it can make the mania even worse. For some people it just upsets the brain chemistry in a way it is not intended ("rare and serious side effects can occur," as the ads state). For me I take a bit of comfort in knowing this really is something within him that I can in no way cure, despite my deep education on it now. The fellow I'm seeing is on a similar drug for PTSD, and it effects him completely differently. The contrast is good to see.

[iamnottheenemy]

Interview with Robert Sapolsky posted on Vox today: https://www.vox.com/conversations/2017/5/23/15516752/science-human-nature-free-will-robert-sapolsky-interview

[kikki]

Bingo.  Always had a sense that Robert Sapolski would be the one to validate our perfect storm/biochemistry theories. 
Well done us. 


"So what is true for the epileptic is true for all of us all of the time? We are our brains and we had no role in the shaping of our biology or our neurology or our chemistry, and yet these are the forces that determine our behavior."

Thanks for posting this IANTE

[1phoenix]

Any one read Quiet?

[Anjae]

Always had a sense that Robert Sapolski would be the one to validate our perfect storm/biochemistry theories. 
Well done us. 

He does validate our perfect storm/biochemistry theories, mas he always strikes me as someone who confuses mechanical actions, typping for example, with thought and chose what t-shirt to wear. I don't think the last two have only to do with biochemestry.

Also, if one is going to put everything down to biochemestry, one will not have right and wrong or good and bad, because, hey, my biochemestry made me do it.

"So what is true for the epileptic is true for all of us all of the time? We are our brains and we had no role in the shaping of our biology or our neurology or our chemistry, and yet these are the forces that determine our behavior."

We had no role in shaping the biology, neurology and chemestry we were born with. Afterwards, we often have a big role shaping how those go, especially neurology and chemestry, the core of human biology is hard to change.

He does, however, mention ambient, history, society, etc as factors that shape those things, so he is aware they can be changed depending of how we were raised/socialized and what type of life we lead (are leading).

[Velika]

Has anyone looked into Huntington's Disease? This seems like an exact description of what I have observed in my former H.

http://web.stanford.edu/group/hopes/cgi-bin/hopes_test/the-behavioral-symptoms-of-huntingtons-disease/

[Velika]

Here is another disorder with a description similar to what we see on this forum.

Depersonalization Disorder:
https://www.google.com/amp/s/amp.theguardian.com/society/2015/sep/04/depersonalisation-disorder-the-condition-youve-never-heard-of-that-affects-millions

[forthetrees]

New article on depression and white matter - structure and function:

http://www.medicalnewstoday.com/articles/318586.php

[Anjae]

From the book Ray has recommended me, and that I am finding very interesting: Daniel J. Siegel, Mindsight


"Like some sleeping medications, alcohol is notorious for being able to shut off the hippocampus temporarily. Alcohol-based “blackouts” are not the same as fainting: The person is awake (though impaired) but does not encode experience into explicit form. People who have blackouts after drinking may not “remember” how they got home, or how they met the person who is in bed with them the next morning.
    Rage can also shut off the hippocampus, and people with out-of-control anger may not be lying when they say they don’t recall what they said or did in that altered state of mind.
    Recent research suggests that other states of high emotion—beyond those we can normally tolerate—may also shut off the hippocampus by way of the high levels of stress they create. Excessive stress-hormone release in a state of terror, for example, may disrupt hippocampal integration."


"Trauma may also shut down the hippocampus temporarily through the mechanism of dissociation. In the face of an overwhelming experience or threat to our survival, when there is no possible physical escape, not only do we release high levels of memory-blocking stress hormones, but the brain may find another form of escape by aiming the narrow channel of focal attention away from the threat. While we don’t yet know exactly how this happens, awareness becomes completely absorbed in some nontraumatic aspect of the environment, or in the interior landscape of the imagination."

[xyzcf]

I saw this on the news tonight...there is so much we do not know about the human brain....this is about how certain people do not respond well to anti depressants and how a test that looks at their genetics can help to determine what medication might be more useful...as well...the dosage is also really important...the recommended dose may not be at all what the person needs.

It is just an example of how different we are and that even with treatment, many people who suffer from depression do not feel better.


http://www.nbcnews.com/health/mental-health/finding-right-medication-gene-test-may-help-treat-depression-n782781

So, treating the MLCer becomes very tricky, especially if they are not open to going for any treatment, let alone finding the right treatment and dosage.